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The Clonal Diversity of Peripheral B Cell Receptor Immune Repertoire Impaired by Residual Malignant B Cells Predicts Treatment Efficacy in B Cell Lymphoma Patients
SIMPLE SUMMARY: This study, for the first time, provided both in-vitro and clinical evidence that established a connection between the presence of residual malignant B cells and the clonal diversity of the resulting BCR repertoire. Lymphoma cells cultured with human germinal center B cells suppresse...
Autores principales: | Wu, Meng, Zhang, Jing, Wang, Yi, Mi, Lan, Wang, Xiaopei, Liu, Weiping, Fu, Jie, Song, Haifeng, Song, Yuqin, Zhu, Jun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9564088/ https://www.ncbi.nlm.nih.gov/pubmed/36230551 http://dx.doi.org/10.3390/cancers14194628 |
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