Salusin-β, a TOR2A gene product, promotes proliferation, migration, fibrosis, and calcification of smooth muscle cells and accelerates the imbalance of vasomotor function and vascular remodeling in monocrotaline-induced pulmonary hypertensive rats

Purpose: The hyper-proliferation, promoted migration, fibrosis, and calcification of pulmonary arterial smooth muscle cells (PASMCs) play critical roles in pulmonary artery (PA) continuous contraction and vascular remodeling, leading to elevated pulmonary arterial resistance and pulmonary hypertensi...

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Detalles Bibliográficos
Autores principales: Wang, Xingxing, Chen, Aidong, Hu, Ruihua, Zhang, Feng, Liang, Shuxin, Bao, Changlei, Liu, Xuanxuan, Tang, Haiyang, Han, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9564106/
https://www.ncbi.nlm.nih.gov/pubmed/36249810
http://dx.doi.org/10.3389/fphar.2022.928834

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9564106/
https://www.ncbi.nlm.nih.gov/pubmed/36249810
http://dx.doi.org/10.3389/fphar.2022.928834

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