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Identification of Monobenzone as a Novel Potential Anti-Acute Myeloid Leukaemia Agent That Inhibits RNR and Suppresses Tumour Growth in Mouse Xenograft Model

SIMPLE SUMMARY: The clinical treatment of acute myeloid leukaemia is still dominated by chemotherapy. Clinically used anti-leukaemia drugs have shortcomings such as myelosuppression, toxicity and drug resistance. Therefore, the need to develop other chemotherapeutic drugs to meet more clinical needs...

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Detalles Bibliográficos
Autores principales: Dong, Jingwen, Zhong, Tingting, Xu, Zhijian, Chen, Haiyi, Wang, Xianjun, Yang, Lili, Lou, Zhiyuan, Xu, Yuanling, Hou, Tingjun, Xu, Rongzhen, Zhu, Weiliang, Shao, Jimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9564123/
https://www.ncbi.nlm.nih.gov/pubmed/36230632
http://dx.doi.org/10.3390/cancers14194710