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Effect of Hypoxia in the Transcriptomic Profile of Lung Fibroblasts from Idiopathic Pulmonary Fibrosis

Idiopathic pulmonary fibrosis (IPF) is an aging-associated disease characterized by exacerbated extracellular matrix deposition that disrupts oxygen exchange. Hypoxia and its transcription factors (HIF-1α and 2α) influence numerous circuits that could perpetuate fibrosis by increasing myofibroblasts...

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Detalles Bibliográficos
Autores principales: Romero, Yair, Balderas-Martínez, Yalbi Itzel, Vargas-Morales, Miguel Angel, Castillejos-López, Manuel, Vázquez-Pérez, Joel Armando, Calyeca, Jazmín, Torres-Espíndola, Luz María, Patiño, Nelly, Camarena, Angel, Carlos-Reyes, Ángeles, Flores-Soto, Edgar, León-Reyes, Guadalupe, Sierra-Vargas, Martha Patricia, Herrera, Iliana, Luis-García, Erika Rubí, Ruiz, Víctor, Velázquez-Cruz, Rafael, Aquino-Gálvez, Arnoldo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9564151/
https://www.ncbi.nlm.nih.gov/pubmed/36230977
http://dx.doi.org/10.3390/cells11193014