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Novel Small Multilamellar Liposomes Containing Large Quantities of Peptide Nucleic Acid Selectively Kill Breast Cancer Cells

SIMPLE SUMMARY: We present, for the first time, the preparation of small (60–90 nm in diameter) liposomes containing extremely large amounts (~8000 molecules per vesicle) of short, cytosine-rich peptide nucleic acid. The outer surface of liposomes wasfunctionalized with scaffold molecules specific t...

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Detalles Bibliográficos
Autores principales: Proshkina, Galina, Shramova, Elena, Ryabova, Anastasiya, Katrivas, Liat, Giannini, Clelia, Malpicci, Daniele, Levi-Kalisman, Yael, Deyev, Sergey, Kotlyar, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9564164/
https://www.ncbi.nlm.nih.gov/pubmed/36230729
http://dx.doi.org/10.3390/cancers14194806