Modulatory Role of TPPP3 in Microtubule Organization and Its Impact on Alpha-Synuclein Pathology

Parkinson’s disease is characterized by locomotion deficits, dopaminergic neuronal loss and alpha-synuclein (SYN) aggregates; the Tubulin Polymerization Promoting Protein (TPPP/p25 or TPPP1) is also implicated in these processes. The moonlighting and chameleon TPPP1 modulates the dynamics/stability...

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Detalles Bibliográficos
Autores principales: Oláh, Judit, Lehotzky, Attila, Szénási, Tibor, Berki, Tímea, Ovádi, Judit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9564178/
https://www.ncbi.nlm.nih.gov/pubmed/36230985
http://dx.doi.org/10.3390/cells11193025

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9564178/
https://www.ncbi.nlm.nih.gov/pubmed/36230985
http://dx.doi.org/10.3390/cells11193025

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