Mitochondrion-Mediated Cell Death through Erk1-Alox5 Independent of Caspase-9 Signaling

Mitochondrial disruption leads to the release of cytochrome c to activate caspase-9 and the downstream caspase cascade for the execution of apoptosis. However, cell death can proceed efficiently in the absence of caspase-9 following mitochondrial disruption, suggesting the existence of caspase-9-ind...

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Detalles Bibliográficos
Autores principales: Chen, Min, Wang, Lei, Li, Min, Budai, Marietta M., Wang, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9564198/
https://www.ncbi.nlm.nih.gov/pubmed/36231015
http://dx.doi.org/10.3390/cells11193053

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9564198/
https://www.ncbi.nlm.nih.gov/pubmed/36231015
http://dx.doi.org/10.3390/cells11193053

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