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Mitochondrion-Mediated Cell Death through Erk1-Alox5 Independent of Caspase-9 Signaling
Mitochondrial disruption leads to the release of cytochrome c to activate caspase-9 and the downstream caspase cascade for the execution of apoptosis. However, cell death can proceed efficiently in the absence of caspase-9 following mitochondrial disruption, suggesting the existence of caspase-9-ind...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9564198/ https://www.ncbi.nlm.nih.gov/pubmed/36231015 http://dx.doi.org/10.3390/cells11193053 |