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Risk Assessment of (Herbal) Teas Containing Pyrrolizidine Alkaloids (PAs) Based on Margin of Exposure Approach and Relative Potency (REP) Factors

Pyrrolizidine alkaloids (PAs) present distinct toxicity potencies depending on their metabolites and in vivo toxicokinetics. To represent the potency differences of various PAs, the interim relative potency (REP) factors have been derived. However, little is known about the risk assessment for (herb...

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Detalles Bibliográficos
Autores principales: Chen, Lu, Zhang, Qian, Yi, Ziwei, Chen, Yu, Xiao, Weihan, Su, Dan, Shi, Wenbiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9564199/
https://www.ncbi.nlm.nih.gov/pubmed/36230022
http://dx.doi.org/10.3390/foods11192946