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Flux coupling, not specificity, shapes the transport and phylogeny of SLC6 glycine transporters

ATB [Formula: see text] (SLC6A14) is a member of the amino acid transporter branch of the SLC6 family along with GlyT1 (SLC6A9) and GlyT2 (SLC6A5), two glycine-specific transporters coupled to 2:1 and 3:1 Na [Formula: see text]:Cl [Formula: see text] , respectively. In contrast, ATB [Formula: see te...

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Detalles Bibliográficos
Autores principales: Le Guellec, Bastien, Rousseau, France, Bied, Marion, Supplisson, Stéphane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9564218/
https://www.ncbi.nlm.nih.gov/pubmed/36191186
http://dx.doi.org/10.1073/pnas.2205874119