Altered Complement System Activity in Schizophrenia: Overexpression of C4 and/or Abnormal Expression of Complement Control Proteins in the DLPFC, Parietal Cortex, Temporal Cortex, Associative Striatum, Hippocampus, Cerebellum and Whole Blood

INTRODUCTION: In schizophrenia, abnormal synaptic pruning during adolescence may be due to an altered Complement system activity. While this hypothesis is supported by C4 overexpression in various brain regions of individuals with schizophrenia, such alterations should be replicated and extended to...

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Detalles Bibliográficos
Autores principales: Rey, R., Leboyer, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2022
Materias:
Abstract
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9564272/
http://dx.doi.org/10.1192/j.eurpsy.2022.930

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9564272/
http://dx.doi.org/10.1192/j.eurpsy.2022.930

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