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Hypoxia-Inducible Expression of Annexin A6 Enhances the Resistance of Triple-Negative Breast Cancer Cells to EGFR and AR Antagonists

Physiological changes such as hypoxia in the tumor microenvironment (TME) endow cancer cells with malignant properties, leading to tumor recurrence and rapid progression. Here, we assessed the effect of hypoxia (1% Oxygen) on the tumor suppressor Annexin A6 (AnxA6) and the response of triple-negativ...

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Detalles Bibliográficos
Autores principales: Williams, Stephen D., Smith, Tunde M., Stewart, LaMonica V., Sakwe, Amos M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9564279/
https://www.ncbi.nlm.nih.gov/pubmed/36230969
http://dx.doi.org/10.3390/cells11193007