Cargando…

Computationally guided conversion of the specificity of E-selectin to mimic that of Siglec-8

Sulfated glycans have been found to be associated with various diseases and therefore have significant potential in molecular pathology as biomarkers. Although lectins are useful reagents for detecting glycans, there is a paucity of sulfate-recognizing lectins, and those that exist, such as from Maa...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Xiaocong, Hanes, Melinda S., Cummings, Richard D., Woods, Robert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9564326/
https://www.ncbi.nlm.nih.gov/pubmed/36191232
http://dx.doi.org/10.1073/pnas.2117743119