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Computationally guided conversion of the specificity of E-selectin to mimic that of Siglec-8
Sulfated glycans have been found to be associated with various diseases and therefore have significant potential in molecular pathology as biomarkers. Although lectins are useful reagents for detecting glycans, there is a paucity of sulfate-recognizing lectins, and those that exist, such as from Maa...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9564326/ https://www.ncbi.nlm.nih.gov/pubmed/36191232 http://dx.doi.org/10.1073/pnas.2117743119 |