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In Silico Strategies for Designing of Peptide Inhibitors of Oncogenic K-Ras G12V Mutant: Inhibiting Cancer Growth and Proliferation

SIMPLE SUMMARY: The most well-known oncogene and one with the highest rates of mutation across all cancers is K-Ras, also known as the Kirsten rat sarcoma viral oncogene homologue. It is also linked to certain cancers with a high mortality rate, including pancreatic ductal adenocarcinoma (PDAC), non...

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Detalles Bibliográficos
Autores principales: Ghufran, Mehreen, Khan, Haider Ali, Ullah, Mehran, Ghufran, Sabreen, Ayaz, Muhammad, Siddiq, Muhammad, Hassan, Syed Shams ul, Bungau, Simona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9564332/
https://www.ncbi.nlm.nih.gov/pubmed/36230807
http://dx.doi.org/10.3390/cancers14194884