Cargando…

Replication stalling activates SSB for recruitment of DNA damage tolerance factors

Translesion synthesis (TLS) polymerases bypass DNA lesions that block replicative polymerases, allowing cells to tolerate DNA damage encountered during replication. It is well known that most bacterial TLS polymerases must interact with the sliding-clamp processivity factor to carry out TLS, but rec...

Descripción completa

Detalles Bibliográficos
Autores principales: Thrall, Elizabeth S., Piatt, Sadie C., Chang, Seungwoo, Loparo, Joseph J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9565051/
https://www.ncbi.nlm.nih.gov/pubmed/36191223
http://dx.doi.org/10.1073/pnas.2208875119