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Mesoscale structure–function relationships in mitochondrial transcriptional condensates

In live cells, phase separation is thought to organize macromolecules into membraneless structures known as biomolecular condensates. Here, we reconstituted transcription in condensates from purified mitochondrial components using optimized in vitro reaction conditions to probe the structure–functio...

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Detalles Bibliográficos
Autores principales: Feric, Marina, Sarfallah, Azadeh, Dar, Furqan, Temiakov, Dmitry, Pappu, Rohit V., Misteli, Tom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9565167/
https://www.ncbi.nlm.nih.gov/pubmed/36191226
http://dx.doi.org/10.1073/pnas.2207303119