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Mesoscale structure–function relationships in mitochondrial transcriptional condensates
In live cells, phase separation is thought to organize macromolecules into membraneless structures known as biomolecular condensates. Here, we reconstituted transcription in condensates from purified mitochondrial components using optimized in vitro reaction conditions to probe the structure–functio...
Autores principales: | Feric, Marina, Sarfallah, Azadeh, Dar, Furqan, Temiakov, Dmitry, Pappu, Rohit V., Misteli, Tom |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9565167/ https://www.ncbi.nlm.nih.gov/pubmed/36191226 http://dx.doi.org/10.1073/pnas.2207303119 |
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