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Integrated 16S rRNA sequencing and metabolomics analysis to investigate the antidepressant role of Yang-Xin-Jie-Yu decoction on microbe-gut-metabolite in chronic unpredictable mild stress-induced depression rat model

Objectives: Our goals were to evaluate the antidepressant efficacy of Yang-Xin-Jie-Yu Decoction (YXJYD) in Chronic Unpredictable Mild Stress (CUMS)-induced depression rat model and to investigate the underlying mechanisms. Design: We used CUMS-induced depression rat model to evaluate whether oral ad...

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Detalles Bibliográficos
Autores principales: Liang, Xing-Qiu, Mai, Peng-Yu, Qin, Hui, Li, Sen, Ou, Wen-Juan, Liang, Jian, Zhong, Jing, Liang, Ming-Kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9565485/
https://www.ncbi.nlm.nih.gov/pubmed/36249818
http://dx.doi.org/10.3389/fphar.2022.972351