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Characterization of a microglia-specific humanized P2X7 receptor knock-out mouse line: Implications for translational psychoneuroimmunology
INTRODUCTION: Depression is a common psychiatric disorder and chronic stress is considered its main environmental risk factor. Recently, immune processes including adenosine triphosphate mediated P2X7 receptor (P2X7R) signalling via microglia and macrophages (M/Ms) were found to play a critical role...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Cambridge University Press
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9565641/ http://dx.doi.org/10.1192/j.eurpsy.2022.937 |