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Machine learning on syngeneic mouse tumor profiles to model clinical immunotherapy response

Most patients with cancer are refractory to immune checkpoint blockade (ICB) therapy, and proper patient stratification remains an open question. Primary patient data suffer from high heterogeneity, low accessibility, and lack of proper controls. In contrast, syngeneic mouse tumor models enable cont...

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Detalles Bibliográficos
Autores principales: Zeng, Zexian, Gu, Shengqing Stan, Wong, Cheryl J., Yang, Lin, Ouardaoui, Nofal, Li, Dian, Zhang, Wubing, Brown, Myles, Liu, X. Shirley
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9565795/
https://www.ncbi.nlm.nih.gov/pubmed/36240281
http://dx.doi.org/10.1126/sciadv.abm8564