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Individual participant data meta-analysis with mixed-effects transformation models

One-stage meta-analysis of individual participant data (IPD) poses several statistical and computational challenges. For time-to-event outcomes, the approach requires the estimation of complicated nonlinear mixed-effects models that are flexible enough to realistically capture the most important cha...

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Detalles Bibliográficos
Autores principales: Tamási, Bálint, Crowther, Michael, Puhan, Milo Alan, Steyerberg, Ewout W, Hothorn, Torsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9566326/
https://www.ncbi.nlm.nih.gov/pubmed/34969073
http://dx.doi.org/10.1093/biostatistics/kxab045