Cargando…

In-silico molecular modelling, MM/GBSA binding free energy and molecular dynamics simulation study of novel pyrido fused imidazo[4,5-c]quinolines as potential anti-tumor agents

With an alarming increase in the number of cancer patients and a variety of tumors, it is high time for intensive investigation on more efficient and potent anti-tumor agents. Though numerous agents have enriched the literature, still there exist challenges, with the availability of different target...

Descripción completa

Detalles Bibliográficos
Autores principales: Dasmahapatra, Upala, Kumar, Chitluri Kiran, Das, Soumyadip, Subramanian, Prathima Thimma, Murali, Poornimaa, Isaac, Arnold Emerson, Ramanathan, Karuppasamy, MM, Balamurali, Chanda, Kaushik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9566731/
https://www.ncbi.nlm.nih.gov/pubmed/36247684
http://dx.doi.org/10.3389/fchem.2022.991369