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Type 1 diabetes: what is the role of autoimmunity in β cell death?

The current dogma of type 1 diabetes pathogenesis asserts that an autoimmune attack leads to the destruction of pancreatic β cells, with subsequent hyperglycemia. This dogma is based on islet autoantibodies emerging prior to the onset of type 1 diabetes. In this issue of the JCI, Warncke et al. repo...

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Detalles Bibliográficos
Autor principal: Donath, Marc Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9566895/
https://www.ncbi.nlm.nih.gov/pubmed/36250460
http://dx.doi.org/10.1172/JCI164460