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Elevated osteopontin and IFNy serum levels and increased neutrophil-to-lymphocyte ratio are associated with the severity of symptoms in schizophrenia

INTRODUCTION: Inflammation and immune dysregulation could contribute to the pathogenesis of schizophrenia. Osteopontin (OPN) is a key cytokine-like molecule in cellular immune response and it can directly modulate the cytokine expression and survival of microglia. Furthermore, its mRNA expression is...

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Detalles Bibliográficos
Autores principales: Kovács, M., Tényi, T., Kugyelka, R., Prenek, L., Herold, R., Balogh, P., Simon, D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9567151/
http://dx.doi.org/10.1192/j.eurpsy.2022.302