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Astersaponin I from Aster koraiensis is a natural viral fusion blocker that inhibits the infection of SARS-CoV-2 variants and syncytium formation

The continuous emergence of SARS-CoV-2 variants prolongs COVID-19 pandemic. Although SARS-CoV-2 vaccines and therapeutics are currently available, there is still a need for development of safe and effective drugs against SARS-CoV-2 and also for preparedness for the next pandemic. Here, we discover t...

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Detalles Bibliográficos
Autores principales: Kim, Tai Young, Kim, Ji-Young, Kwon, Hak Cheol, Jeon, Sangeun, Lee, Sol ji, Jung, Haejin, Kim, Seungtaek, Jang, Dae Sik, Lee, C Justin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9568284/
https://www.ncbi.nlm.nih.gov/pubmed/36252824
http://dx.doi.org/10.1016/j.antiviral.2022.105428