Distinct roles for CKM–Mediator in controlling Polycomb-dependent chromosomal interactions and priming genes for induction

Precise control of gene expression underpins normal development. This relies on mechanisms that enable communication between gene promoters and other regulatory elements. In embryonic stem cells (ESCs), the cyclin-dependent kinase module Mediator complex (CKM–Mediator) has been reported to physicall...

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Detalles Bibliográficos
Autores principales: Dimitrova, Emilia, Feldmann, Angelika, van der Weide, Robin H., Flach, Koen D., Lastuvkova, Anna, de Wit, Elzo, Klose, Robert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9568430/
https://www.ncbi.nlm.nih.gov/pubmed/36220895
http://dx.doi.org/10.1038/s41594-022-00840-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9568430/
https://www.ncbi.nlm.nih.gov/pubmed/36220895
http://dx.doi.org/10.1038/s41594-022-00840-5

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