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Distinct roles for CKM–Mediator in controlling Polycomb-dependent chromosomal interactions and priming genes for induction
Precise control of gene expression underpins normal development. This relies on mechanisms that enable communication between gene promoters and other regulatory elements. In embryonic stem cells (ESCs), the cyclin-dependent kinase module Mediator complex (CKM–Mediator) has been reported to physicall...
Autores principales: | Dimitrova, Emilia, Feldmann, Angelika, van der Weide, Robin H., Flach, Koen D., Lastuvkova, Anna, de Wit, Elzo, Klose, Robert J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group US
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9568430/ https://www.ncbi.nlm.nih.gov/pubmed/36220895 http://dx.doi.org/10.1038/s41594-022-00840-5 |
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