Anabolic actions of parathyroid hormone in a hypophosphatasia mouse model

SUMMARY: Hypophosphatasia, the rare heritable disorder caused by TNAP enzyme mutations, presents wide-ranging severity of bone hypomineralization and skeletal abnormalities. Intermittent PTH (1-34) increased long bone volume in Alpl(-/-) mice but did not alter the skull phenotype. PTH may have thera...

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Detalles Bibliográficos
Autores principales: Koh, Amy J, Nam, Hwa Kyung, Michalski, Megan N, Do, Justin, McCauley, Laurie K, Hatch, Nan E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer London 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9568459/
https://www.ncbi.nlm.nih.gov/pubmed/35871207
http://dx.doi.org/10.1007/s00198-022-06496-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9568459/
https://www.ncbi.nlm.nih.gov/pubmed/35871207
http://dx.doi.org/10.1007/s00198-022-06496-7

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