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Anabolic actions of parathyroid hormone in a hypophosphatasia mouse model
SUMMARY: Hypophosphatasia, the rare heritable disorder caused by TNAP enzyme mutations, presents wide-ranging severity of bone hypomineralization and skeletal abnormalities. Intermittent PTH (1-34) increased long bone volume in Alpl(-/-) mice but did not alter the skull phenotype. PTH may have thera...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer London
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9568459/ https://www.ncbi.nlm.nih.gov/pubmed/35871207 http://dx.doi.org/10.1007/s00198-022-06496-7 |