Identification of in vivo roles of ErbB4-JMa and its direct nuclear signaling using a novel isoform-specific knock out mouse

Like all receptor tyrosine kinases (RTKs), ErbB4 signals through a canonical signaling involving phosphorylation cascades. However, ErbB4 can also signal through a non-canonical mechanism whereby the intracellular domain is released into the cytoplasm by regulated intramembrane proteolysis (RIP) and...

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Detalles Bibliográficos
Autores principales: Doherty, Robert, MacLeod, Brenna L., Nelson, Megan M., Ibrahim, Mostafa M. H., Borges, Beatriz C., Jaradat, Nada W., Finneran, Matthew C., Giger, Roman J., Corfas, Gabriel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9568506/
https://www.ncbi.nlm.nih.gov/pubmed/36241655
http://dx.doi.org/10.1038/s41598-022-21598-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9568506/
https://www.ncbi.nlm.nih.gov/pubmed/36241655
http://dx.doi.org/10.1038/s41598-022-21598-2

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