Rapid differentiation of hiPSCs into functional oligodendrocytes using an OLIG2 synthetic modified messenger RNA

Transcription factors (TFs) have been introduced to drive the highly efficient differentiation of human-induced pluripotent stem cells (hiPSCs) into lineage-specific oligodendrocytes (OLs). However, effective strategies currently rely mainly on genome-integrating viruses. Here we show that a synthet...

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Detalles Bibliográficos
Autores principales: Xu, Jian, Yang, Zhihua, Wang, Rui, He, Fumei, Yan, Rong, Zhang, Yidi, Yu, Liying, Deng, Wenbin, Nie, Yichu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9568531/
https://www.ncbi.nlm.nih.gov/pubmed/36241911
http://dx.doi.org/10.1038/s42003-022-04043-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9568531/
https://www.ncbi.nlm.nih.gov/pubmed/36241911
http://dx.doi.org/10.1038/s42003-022-04043-y

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