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Rapid differentiation of hiPSCs into functional oligodendrocytes using an OLIG2 synthetic modified messenger RNA

Transcription factors (TFs) have been introduced to drive the highly efficient differentiation of human-induced pluripotent stem cells (hiPSCs) into lineage-specific oligodendrocytes (OLs). However, effective strategies currently rely mainly on genome-integrating viruses. Here we show that a synthet...

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Detalles Bibliográficos
Autores principales:	Xu, Jian, Yang, Zhihua, Wang, Rui, He, Fumei, Yan, Rong, Zhang, Yidi, Yu, Liying, Deng, Wenbin, Nie, Yichu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9568531/ https://www.ncbi.nlm.nih.gov/pubmed/36241911 http://dx.doi.org/10.1038/s42003-022-04043-y

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