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Structure of the core human NADPH oxidase NOX2

NOX2 is the prototypical member of the NADPH oxidase NOX superfamily and produces superoxide (O(2)(•−)), a key reactive oxygen species (ROS) that is essential in innate and adaptive immunity. Mutations that lead to deficiency in NOX2 activity correlate with increased susceptibility to bacterial and...

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Detalles Bibliográficos
Autores principales: Noreng, Sigrid, Ota, Naruhisa, Sun, Yonglian, Ho, Hoangdung, Johnson, Matthew, Arthur, Christopher P., Schneider, Kellen, Lehoux, Isabelle, Davies, Christopher W., Mortara, Kyle, Wong, Kit, Seshasayee, Dhaya, Masureel, Matthieu, Payandeh, Jian, Yi, Tangsheng, Koerber, James T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9568551/
https://www.ncbi.nlm.nih.gov/pubmed/36241643
http://dx.doi.org/10.1038/s41467-022-33711-0