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Structure of the core human NADPH oxidase NOX2
NOX2 is the prototypical member of the NADPH oxidase NOX superfamily and produces superoxide (O(2)(•−)), a key reactive oxygen species (ROS) that is essential in innate and adaptive immunity. Mutations that lead to deficiency in NOX2 activity correlate with increased susceptibility to bacterial and...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9568551/ https://www.ncbi.nlm.nih.gov/pubmed/36241643 http://dx.doi.org/10.1038/s41467-022-33711-0 |