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Ion transfer mechanisms in Mrp-type antiporters from high resolution cryoEM and molecular dynamics simulations

Multiple resistance and pH adaptation (Mrp) cation/proton antiporters are essential for growth of a variety of halophilic and alkaliphilic bacteria under stress conditions. Mrp-type antiporters are closely related to the membrane domain of respiratory complex I. We determined the structure of the Mr...

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Detalles Bibliográficos
Autores principales: Lee, Yongchan, Haapanen, Outi, Altmeyer, Anton, Kühlbrandt, Werner, Sharma, Vivek, Zickermann, Volker
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9568556/
https://www.ncbi.nlm.nih.gov/pubmed/36241630
http://dx.doi.org/10.1038/s41467-022-33640-y