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Ion transfer mechanisms in Mrp-type antiporters from high resolution cryoEM and molecular dynamics simulations
Multiple resistance and pH adaptation (Mrp) cation/proton antiporters are essential for growth of a variety of halophilic and alkaliphilic bacteria under stress conditions. Mrp-type antiporters are closely related to the membrane domain of respiratory complex I. We determined the structure of the Mr...
Autores principales: | Lee, Yongchan, Haapanen, Outi, Altmeyer, Anton, Kühlbrandt, Werner, Sharma, Vivek, Zickermann, Volker |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9568556/ https://www.ncbi.nlm.nih.gov/pubmed/36241630 http://dx.doi.org/10.1038/s41467-022-33640-y |
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