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Opposing functions of circadian protein DBP and atypical E2F family E2F8 in anti-tumor Th9 cell differentiation

Interleukin-9 (IL-9)-producing CD4(+) T helper cells (Th9) have been implicated in allergy/asthma and anti-tumor immunity, yet molecular insights on their differentiation from activated T cells, driven by IL-4 and transforming growth factor-beta (TGF-β), is still lacking. Here we show opposing funct...

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Detalles Bibliográficos
Autores principales: Park, Sang-A, Lim, Yun-Ji, Ku, Wai Lim, Zhang, Dunfang, Cui, Kairong, Tang, Liu-Ya, Chia, Cheryl, Zanvit, Peter, Chen, Zuojia, Jin, Wenwen, Wang, Dandan, Xu, Junji, Liu, Ousheng, Wang, Fu, Cain, Alexander, Guo, Nancy, Nakatsukasa, Hiroko, Wu, Chuan, Zhang, Ying E., Zhao, Keji, Chen, WanJun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9568563/
https://www.ncbi.nlm.nih.gov/pubmed/36241625
http://dx.doi.org/10.1038/s41467-022-33733-8