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Hemipiperazines as peptide-derived molecular photoswitches with low-nanomolar cytotoxicity
Molecular photoswitches transform light energy into reversible structural changes. Their combination with known pharmacophores often allows for photomodulation of the biological activity. The effort to apply such compounds in photopharmacology as light-activated pro-drugs is, however, hampered by se...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9568564/ https://www.ncbi.nlm.nih.gov/pubmed/36241620 http://dx.doi.org/10.1038/s41467-022-33750-7 |