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Hemipiperazines as peptide-derived molecular photoswitches with low-nanomolar cytotoxicity

Molecular photoswitches transform light energy into reversible structural changes. Their combination with known pharmacophores often allows for photomodulation of the biological activity. The effort to apply such compounds in photopharmacology as light-activated pro-drugs is, however, hampered by se...

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Detalles Bibliográficos
Autores principales: Kirchner, Susanne, Leistner, Anna-Lena, Gödtel, Peter, Seliwjorstow, Angelika, Weber, Sven, Karcher, Johannes, Nieger, Martin, Pianowski, Zbigniew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9568564/
https://www.ncbi.nlm.nih.gov/pubmed/36241620
http://dx.doi.org/10.1038/s41467-022-33750-7