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Nanoparticle-based modulation of CD4(+) T cell effector and helper functions enhances adoptive immunotherapy
Helper (CD4(+)) T cells perform direct therapeutic functions and augment responses of cells such as cytotoxic (CD8(+)) T cells against a wide variety of diseases and pathogens. Nevertheless, inefficient synthetic technologies for expansion of antigen-specific CD4(+) T cells hinders consistency and s...
Autores principales: | , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9568616/ https://www.ncbi.nlm.nih.gov/pubmed/36241639 http://dx.doi.org/10.1038/s41467-022-33597-y |