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Nanoparticle-based modulation of CD4(+) T cell effector and helper functions enhances adoptive immunotherapy

Helper (CD4(+)) T cells perform direct therapeutic functions and augment responses of cells such as cytotoxic (CD8(+)) T cells against a wide variety of diseases and pathogens. Nevertheless, inefficient synthetic technologies for expansion of antigen-specific CD4(+) T cells hinders consistency and s...

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Detalles Bibliográficos
Autores principales:	Isser, Ariel, Silver, Aliyah B., Pruitt, Hawley C., Mass, Michal, Elias, Emma H., Aihara, Gohta, Kang, Si-Sim, Bachmann, Niklas, Chen, Ying-Yu, Leonard, Elissa K., Bieler, Joan G., Chaisawangwong, Worarat, Choy, Joseph, Shannon, Sydney R., Gerecht, Sharon, Weber, Jeffrey S., Spangler, Jamie B., Schneck, Jonathan P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9568616/ https://www.ncbi.nlm.nih.gov/pubmed/36241639 http://dx.doi.org/10.1038/s41467-022-33597-y

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