Cargando…

DNA methylation at birth in monozygotic twins discordant for pediatric acute lymphoblastic leukemia

Aberrant DNA methylation constitutes a key feature of pediatric acute lymphoblastic leukemia at diagnosis, however its role as a predisposing or early contributor to leukemia development remains unknown. Here, we evaluate DNA methylation at birth in 41 leukemia-discordant monozygotic twin pairs usin...

Descripción completa

Detalles Bibliográficos
Autores principales: Nickels, Eric M., Li, Shaobo, Myint, Swe Swe, Arroyo, Katti, Feng, Qianxi, Siegmund, Kimberly D., de Smith, Adam J., Wiemels, Joseph L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9568651/
https://www.ncbi.nlm.nih.gov/pubmed/36241624
http://dx.doi.org/10.1038/s41467-022-33677-z