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DNA methylation at birth in monozygotic twins discordant for pediatric acute lymphoblastic leukemia
Aberrant DNA methylation constitutes a key feature of pediatric acute lymphoblastic leukemia at diagnosis, however its role as a predisposing or early contributor to leukemia development remains unknown. Here, we evaluate DNA methylation at birth in 41 leukemia-discordant monozygotic twin pairs usin...
Autores principales: | Nickels, Eric M., Li, Shaobo, Myint, Swe Swe, Arroyo, Katti, Feng, Qianxi, Siegmund, Kimberly D., de Smith, Adam J., Wiemels, Joseph L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9568651/ https://www.ncbi.nlm.nih.gov/pubmed/36241624 http://dx.doi.org/10.1038/s41467-022-33677-z |
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