Essential role of TMPRSS2 in SARS-CoV-2 infection in murine airways

In cultured cells, SARS-CoV-2 infects cells via multiple pathways using different host proteases. Recent studies have shown that the furin and TMPRSS2 (furin/TMPRSS2)-dependent pathway plays a minor role in infection of the Omicron variant. Here, we confirm that Omicron uses the furin/TMPRSS2-depend...

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Detalles Bibliográficos
Autores principales: Iwata-Yoshikawa, Naoko, Kakizaki, Masatoshi, Shiwa-Sudo, Nozomi, Okura, Takashi, Tahara, Maino, Fukushi, Shuetsu, Maeda, Ken, Kawase, Miyuki, Asanuma, Hideki, Tomita, Yuriko, Takayama, Ikuyo, Matsuyama, Shutoku, Shirato, Kazuya, Suzuki, Tadaki, Nagata, Noriyo, Takeda, Makoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9568946/
https://www.ncbi.nlm.nih.gov/pubmed/36243815
http://dx.doi.org/10.1038/s41467-022-33911-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9568946/
https://www.ncbi.nlm.nih.gov/pubmed/36243815
http://dx.doi.org/10.1038/s41467-022-33911-8

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