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Discriminating cross-reactivity in polyclonal IgG1 responses against SARS-CoV-2 variants of concern

Existing assays to measure antibody cross-reactivity against different SARS-CoV-2 spike (S) protein variants lack the discriminatory power to provide insights at the level of individual clones. Using a mass spectrometry-based approach we are able to monitor individual donors’ IgG1 clonal responses f...

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Detalles Bibliográficos
Autores principales: van Rijswijck, Danique M. H., Bondt, Albert, Hoek, Max, van der Straten, Karlijn, Caniels, Tom G., Poniman, Meliawati, Eggink, Dirk, Reusken, Chantal, de Bree, Godelieve J., Sanders, Rogier W., van Gils, Marit J., Heck, Albert J. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9568977/
https://www.ncbi.nlm.nih.gov/pubmed/36243713
http://dx.doi.org/10.1038/s41467-022-33899-1