The long non-coding RNA SPRIGHTLY and its binding partner PTBP1 regulate exon 5 skipping of SMYD3 transcripts in group 4 medulloblastomas

BACKGROUND: Although some of the regulatory genes, signaling pathways, and gene regulatory networks altered in medulloblastomas (MB) are known, the roles of non-coding RNAs, particularly long non-coding RNAs (lncRNAs), are poorly described. Here we report that the lncRNA SPRIGHTLY (SPRY4-IT1) gene i...

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Detalles Bibliográficos
Autores principales: Lee, Bongyong, Katsushima, Keisuke, Pokhrel, Rudramani, Yuan, Menglang, Stapleton, Stacie, Jallo, George, Wechsler-Reya, Robert J, Eberhart, Charles G, Ray, Animesh, Perera, Ranjan J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Basic and Translational Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9569026/
https://www.ncbi.nlm.nih.gov/pubmed/36267874
http://dx.doi.org/10.1093/noajnl/vdac120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9569026/
https://www.ncbi.nlm.nih.gov/pubmed/36267874
http://dx.doi.org/10.1093/noajnl/vdac120

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