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Circular RNA circ_0008365 regulates SOX9 by targeting miR-338-3p to inhibit IL-1β-induced chondrocyte apoptosis and extracellular matrix degradation

BACKGROUND: Osteoarthritis (OA) is a chronic disease that involves chondrocyte injury and dysfunction. CircRNAs participate in OA progression, but the roles of circRNAs in the occurrence of OA are unclear. In this study, we explore the role of circ_0008365 in OA. METHODS: CHON-001 cells were treated...

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Detalles Bibliográficos
Autores principales: Shuai, Shengbin, Cai, Qianqian, Ou, Yunxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9569125/
https://www.ncbi.nlm.nih.gov/pubmed/36242088
http://dx.doi.org/10.1186/s13018-022-03240-z