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CircCRIM1 Ameliorates Endothelial Cell Angiogenesis in Aging through the miR-455-3p/Twist1/VEGFR2 Signaling Axis

BACKGROUND: Aging leads to vascular endothelial cell senescence. Decreased expression of VEGFA and VEGFR2 plays a crucial role in impairing angiogenesis in senescent endothelial cells. Noncoding RNAs, including circular RNAs (circRNAs) and microRNAs (miRNAs), regulate endothelial cell proliferation,...

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Detalles Bibliográficos
Autores principales: Zhao, Lei, Chen, Rencong, Qiu, Jiacong, Huang, Yingxiong, Lian, Chong, Zhu, Xiaonan, Cui, Jin, Wang, Siwen, Wang, Shenming, Hu, Zuojun, Wang, Jinsong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9569221/
https://www.ncbi.nlm.nih.gov/pubmed/36254231
http://dx.doi.org/10.1155/2022/2062885