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Regulation of UHRF1 acetylation by TIP60 is important for colon cancer cell proliferation

BACKGROUND: Ubiquitin-like with PHD and RING finger domains 1 (UHRF1) is upregulated in colon cancer cells and associated with silencing tumor suppressor genes (TSGs) to promote colon cancer cell proliferation. OBJECTIVE: To investigate epigenetic modification of UHRF1 by TIP60. Whether UHRF1 acetyl...

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Detalles Bibliográficos
Autores principales: Hong, Ye Joo, Park, Junyoung, Hahm, Ja Young, Kim, Song Hyun, Lee, Dong Ho, Park, Kwon-Sik, Seo, Sang-Beom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9569301/
https://www.ncbi.nlm.nih.gov/pubmed/35951156
http://dx.doi.org/10.1007/s13258-022-01298-x