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Combining OSMAC, metabolomic and genomic methods for the production and annotation of halogenated azaphilones and ilicicolins in termite symbiotic fungi

We gathered a collection of termite mutualistic strains from French Guiana to explore the metabolites of symbiotic microorganisms. Molecular networks reconstructed from a metabolomic analysis using LC–ESI–MS/MS methodology led us to identify two families of chlorinated polyketides, i.e., azaphilones...

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Detalles Bibliográficos
Autores principales: Hebra, Téo, Pollet, Nicolas, Touboul, David, Eparvier, Véronique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9569342/
https://www.ncbi.nlm.nih.gov/pubmed/36243836
http://dx.doi.org/10.1038/s41598-022-22256-3