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Single-molecule tracking of Nodal and Lefty in live zebrafish embryos supports hindered diffusion model
The hindered diffusion model postulates that the movement of a signaling molecule through an embryo is affected by tissue geometry and binding-mediated hindrance, but these effects have not been directly demonstrated in vivo. Here, we visualize extracellular movement and binding of individual molecu...
Autores principales: | Kuhn, Timo, Landge, Amit N., Mörsdorf, David, Coßmann, Jonas, Gerstenecker, Johanna, Čapek, Daniel, Müller, Patrick, Gebhardt, J. Christof M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9569377/ https://www.ncbi.nlm.nih.gov/pubmed/36243734 http://dx.doi.org/10.1038/s41467-022-33704-z |
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